1 edition of International Review of Neurobiology, 21 found in the catalog.
INTERNATIONAL REVIEW NEUROBIOLOGY V 21.
Description based on print version record.
|LC Classifications||RC341 .I5 1979|
|The Physical Object|
|Pagination||1 online resource (427 p.)|
|Number of Pages||427|
An investigation of intravenous ethanol self-administration in rats using a fixed ratio schedule of reinforcement. A] receptor antagonists as well as compounds that stimulate the [GABA. Such increasingly quantitative work gave rise to numerous biological neuron models and models of neural computation. Generalization of behaviorally augmented tolerance to ethanol, and its relation to physical dependence. Journal of-Neuroscience 20 5
In: Thurman, R. Psychopharmacologia 44 3 Annals of Medicine 22 5 Performance and reliability cookies These cookies allow us to monitor OverDrive's performance and reliability.
The prefrontal cortex and, particularly, the orbitofrontal cortex 7 have central roles in executive functions, such as decisionmaking. Thus, people may drink to prevent or alleviate the anxiety they experience during alcohol withdrawal. The roles of these molecules in impulse conduction and synaptic transmission are fully explained, and illustrated by computer models. Interestingly, this procedure is used primarily with mice because they exhibit a preference for alcohol-paired environments, whereas rats typically exhibit an aversion to environments that previously were paired with alcohol Cunningham et al. Excessive ethanol drinking following a history of dependence: Animal model of allostasis.
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Journal of Neuroscience 16 10 That behavior then is extinguished-that is, the animal no longer receives alcohol for pressing a lever until the animal no longer attempts to press the lever at all.
In addition to the extant literature on the importance of brain reward circuits in the development of alcohol dependence, recent research has focused on a new contingent of neural systems that play central roles in the regulation of stress and anxiety as well as mediate executive functions.
Researchers can then examine the propensity of animals to relapse to alcohol-seeking behavior under three conditions that mimic the human situation: 1 following administration of a small "priming" dose of alcohol, 2 following exposure to environmental cues previously associated with alcohol, and 3 following exposure to stressors.
This pattern of self-administration, defined in humans as an excessive pattern of alcohol drinking that produces blood alcohol levels greater than 0. Additive effect of stress and drug cues on reinstatement of ethanol seeking: Exacerbation by history of dependence and role of concurrent activation of corticotropin-releasing factor and opioid mechanisms.
For example, it has become possible to understand, in much detail, the complex processes occurring within a single neuron. Adapted from Shebani et al. Once neuroadaptation has occurred, removal of alcohol from the organism leads to a withdrawal syndrome.
Proceedings 1, pp. They are able to communicate with neurons and other cell types through specialized junctions 21 book synapsesat which electrical or electrochemical signals can be transmitted from one cell to another.
In many species — including all International Review of Neurobiology — the nervous system is the most complex organ system in the body, with most of the complexity residing in the brain. A] receptors Sanna et al.
The relation between alcohol problems and the anxiety disorders. Tolerance An organism that is chronically exposed to alcohol develops tolerance to its functional e. For more information on nerve signal transmission, neurotransmitters, and their receptors, see the article by Lovinger, pp.
Alcoholism: Allostasis and beyond. There are three classes of endogenous opioids: endorphins, enkephalins, and dynorphins. Numerous other stress-related systems exist that may be important in the development of alcohol dependence, including those involving norepinephrine, orexin hypocretinvasopressin, dynorphin, nociceptin orphanin FQneuropeptide-S, and neurokinin; an extensive overview of these systems can be found elsewhere Koob Moreover, the clearance of alcohol from the body of an individual with high tolerance can produce a withdrawal syndrome defined by symptoms that are largely the opposite of the effects of alcohol itself.
Chronic alcohol vapor inhalation results in enhanced alcohol-reinforced behavior that lasts well beyond the dissipation of acute withdrawal symptoms Gilpin et al.
Operant conditioning procedures can be fine-tuned to include different work requirements for stimuli with varying degrees of motivational value for the individual tested.
The Encyclopedia of Human Behavior, vol. Multiple processes contribute to the increased motivation to seek drugs during the development of dependence. Brain Impulsivity resulting from frontostriatal dysfunction in drug abuse: Implications for the control of behavior by reward-related stimuli.
Authors submitting papers after this date will be requested to pay the APC. Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: Genetic and motivational determinants.
Table of Contents. Another method for assessing the reinforcing properties of alcohol is intracranial self-stimulation ICSS. Alcoholism: Clinical and Experimental Research 26 8International Review of Neurobiology, Volume Medicine & Health Science Books @ sylvaindez.com Books Advanced Search New Releases Best Sellers & More Children's Books Textbooks Textbook Rentals Sell Us Your Books Best Books of the Month.
Ronald J. Bradley is the author of International Review of Neurobiology, Volume 73 ( avg rating, 0 ratings, 0 reviews, published ), International Home My Books5/5(1).
Databases E-Journals & E-Books Orbis (Library Catalog) Quicksearch Services Library Technology Mobile Device Applications Places to Study & Collaborate Printing, Photocopying, Scanning Report an Access Problem Request Materials Reserve Study Rooms. Neurobiology of Disease 2nd Edition The second edition of Neurobiology of Disease includes nearly articles surveying all major disorders of the nervous system in both adults and children, focusing on relevant diagnosis and treatments from the perspective of.
Oct 22, · Purchase International Review of Neurobiology - 1st Edition. Print Book & E-Book. ISBNSkip to content. International Review of Neurobiology, Supplement 1: Neurobiology of the Trace Metals Zinc and Copper represents a first report in the study of the neurobiology of zinc and copper.
Book Edition: 1. Dr. Konopka is an Associate Professor of Neuroscience and the Jon Heighten Scholar in Autism Research at UT Southwestern Medical Center. Dr. Konopka received dual bachelor of science degrees in Brain and Cognitive Sciences and Biology from MIT and completed her Ph.D.
in Neurobiology at Harvard University.